Book Metadata
- Full Title: Merritt’s Neurology, Fourteenth Edition
- Editors: Elan D. Louis, MD, MS; Stephan A. Mayer, MD, FCCM, FNCS; and James M. Noble, MD, MS, CPH, FAAN
- Authors: More than 180 world-recognized expert contributors
- Year of Publication: 2022
- Total Number of Pages: 5907 pages.
Copyright Summary
This Fourteenth Edition is published by Wolters Kluwer and carries the copyright date of 2022. The work is identified by multiple ISBNs, including 9781975141226 for the hardcover edition and 9781975141233 for the eBook. Legal notices specify that the book is a reference tool and not a substitute for independent professional assessment or medical judgment, provided "as is" without warranties regarding the currency or accuracy of the content.
Preface Analysis: Modernizing a Global Classic
The editors intended to modernize this classic text by expanding its authorship to over 180 experts and adopting a "global worldview" regarding the burden of neurologic disease. The book aims to fill a clinical gap created by the "rapidly advancing" nature of neurology and the difficulty clinicians face when sorting through unverified information on the internet.
By consolidating research, new treatments for previously untreatable diseases, and evidence-based guidelines into a single cohesive source, the book serves as a "curated, clinically rich" tool for use at the bedside, in the office, or during virtual clinical sessions. The intended primary audience includes trainees (residents), academic neurologists, and practicing clinicians worldwide.
Chapter List
SECTION I: GLOBAL BURDEN OF NEUROLOGIC DISEASE
- 1: Worldwide Epidemiology of Neurologic Disease
- 2: Global Delivery of Neurologic Care
SECTION II: APPROACH TO THE NEUROLOGIC PATIENT
- 3: Neurologic History Taking, Localization, and Differential Diagnosis
- 4: The Neurologic Examination
SECTION III: COMMON PROBLEMS IN NEUROLOGY
- 5: Dizziness, Vertigo, and Hearing Loss
- 6: Syncope
- 7: Seizures
- 8: Pain, Numbness, and Paresthesias
- 9: Headache and Facial Pain
- 10: Visual Disturbances
- 11: Delirium
- 12: Dementia and Memory Loss
- 13: Involuntary Movements
- 14: Muscle Weakness, Cramps, and Stiffness
- 15: Gait Disorders
- 16: Acute Stroke: The First Hour
- 17: Acute Spinal Cord Syndromes
- 18: Focal Mass Lesions
- 19: Stupor and Coma
- 20: Brain Death
SECTION IV: DIAGNOSTIC TESTS
- 21: Computed Tomography
- 22: Magnetic Resonance Imaging
- 23: Ultrasound
- 24: Neuroangiography and Neuroendovascular Surgery
- 25: Electroencephalography and Evoked Potentials
- 26: Magnetoencephalography
- 27: Electromyography, Nerve Conduction Studies, and Magnetic Stimulation
- 28: Autonomic Testing
- 29: Evaluation of the Special Senses (Vision, Hearing, Smell, Vestibular System)
- 30: Sleep Studies
- 31: Neuropsychological Evaluation
- 32: Lumbar Puncture and Cerebrospinal Fluid Analysis
- 33: Brain, Muscle, Nerve, and Skin Biopsy
- 34: Intracranial Pressure and Neurocritical Care Monitoring
- 35: Genetic Testing and DNA Diagnosis
SECTION V: CEREBROVASCULAR DISEASES
- 36: Acute Ischemic Stroke
- 37: Transient Ischemic Attack
- 38: Hypoxic-Ischemic Encephalopathy
- 39: Intracerebral Hemorrhage
- 40: Subarachnoid Hemorrhage
- 41: Cerebral Venous and Sinus Thrombosis
- 42: Vascular Malformations
- 43: Central Nervous System Vasculitis
- 44: Other Cerebrovascular Syndromes
- 45: Primary and Secondary Stroke Prevention
SECTION VI: NEUROTRAUMA
- 46: Concussion and Chronic Traumatic Encephalopathy
- 47: Traumatic Brain Injury
- 48: Traumatic Spinal Cord Injury
- 49: Traumatic Cranial and Peripheral Nerve Injury
SECTION VII: DEMENTIA
- 50: Mild Cognitive Impairment
- 51: Alzheimer's Disease
- 52: Frontotemporal Dementia
- 53: Lewy Body Dementias
- 54: Vascular Dementia and Cognitive Impairment
- 55: Prion Diseases
SECTION VIII: HEADACHE AND PAIN SYNDROMES
- 56: Primary and Secondary Headache Disorders
- 57: Facial Pain Disorders and Painful Cranial Neuralgias
- 58: Complex Regional Pain Syndrome
- 59: Neuropathic Pain
SECTION IX: EPILEPSY AND PAROXYSMAL DISORDERS
- 60: Classification of Seizures and Epilepsy
- 61: Treatment of Epilepsy
- 62: Ménière Syndrome, Benign Paroxysmal Positional Vertigo, and Vestibular Neuritis
- 63: Transient Global Amnesia
SECTION X: CENTRAL NERVOUS SYSTEM INFECTIONS
- 64: Acute Bacterial Meningitis
- 65: Brain, Spinal, and Epidural Abscess and Other Parameningeal Infections
- 66: Other Bacterial Central Nervous System Infections and Toxins
- 67: Chronic Meningitis
- 68: Parasitic Infections
- 69: Viral Infections
- 70: Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS)
SECTION XI: DEMYELINATING AND INFLAMMATORY DISEASES
- 71: Multiple Sclerosis and Related CNS Neuroimmune Diseases
- 72: Transverse Myelitis
- 73: Neuromyelitis Optica Spectrum Disorder
- 74: Autoimmune Encephalitis and Meningitis
- 75: Neurosarcoidosis
SECTION XII: MOVEMENT DISORDERS
- 76: Essential Tremor
- 77: Tics and Tourette Syndrome
- 78: Restless Legs Syndrome
- 79: The Dystonias
- 80: Hemifacial Spasm
- 81: Myoclonus
- 82: Hereditary and Acquired Ataxias
- 83: Tardive Dyskinesia and Other Neuroleptic-Induced Syndromes
- 84: Choreas
- 85: Huntington's Disease
- 86: Parkinson's Disease
- 87: Parkinson-Plus Syndromes
SECTION XIII: NEUROMUSCULAR DISEASES
- 88: Amyotrophic Lateral Sclerosis and Motor Neuron Diseases
- 89: Bell’s Palsy and Cranial Neuropathies
- 90: Mononeuropathies and Compression Neuropathies
- 91: Acquired Peripheral Neuropathies
- 92: Inherited Peripheral Neuropathies
- 93: Myasthenia Gravis and Other Disorders of the Neuromuscular Junction
- 94: Inflammatory and Autoimmune Myopathies
- 95: Critical Illness Myopathy and Neuropathy
- 96: Endocrine and Toxic Myopathies
- 97: Periodic Paralysis and Other Channelopathies
- 98: Stiff Person Syndrome and Peripheral Nerve and Muscle Hyperexcitability
- 99: Metabolic and Mitochondrial Myopathies in Adults
SECTION XIV: NEUROONCOLOGY
- 100: Gliomas
- 101: Metastatic Tumors
- 102: Meningiomas
- 103: Primary Central Nervous System Lymphoma
- 104: Tumors of the Pituitary Gland
- 105: Pineal Region Tumors
- 106: Acoustic Neuroma and Other Skull Base Tumors
- 107: Spinal Tumors
- 108: Paraneoplastic Syndromes
- 109: Complications of Cancer Therapy
SECTION XV: HYDROCEPHALUS AND CEREBRAL EDEMA
- 110: Hydrocephalus
- 111: Brain Edema and Increased Intracranial Pressure
- 112: Spontaneous Intracranial Hypotension
SECTION XVI: SPINAL CORD DISORDERS
- 113: Intervertebral Disk Disease and Radiculopathy
- 114: Cervical and Lumbar Spinal Stenosis
- 115: Acquired and Hereditary Myelopathies
SECTION XVII: AUTONOMIC AND SLEEP DISTURBANCES
- 116: Autonomic Failure, Autonomic Neuropathy, and Orthostatic Intolerance
- 117: Paroxysmal Sympathetic Hyperactivity After Acute Brain Injury
- 118: Sleep Disorders
SECTION XVIII: SYSTEMIC ORGAN FUNCTION AND THE NERVOUS SYSTEM
- 119: Heart-Brain Interactions
- 120: Sepsis-Associated Encephalopathy
- 121: Respiratory Support for Neurologic Diseases
- 122: Endocrine Diseases and the Brain
- 123: Hematologic Diseases and the Brain
- 124: Hepatic Disease and the Brain
- 125: Renal Disease, Electrolyte Disorders, and the Nervous System
- 126: Gastric and Genitourinary Function and the Brain
- 127: Bone Diseases and the Central Nervous System
- 128: Malnutrition, Malabsorption, and Vitamin Deficiencies
- 129: Neurologic Disease During Pregnancy
- 130: Neurologic Complications of Organ Transplantation
SECTION XIX: NEUROLOGIC TOXIDROMES
- 131: Alcoholism
- 132: Drug Intoxication and Withdrawal
- 133: Neurotoxicology
- 134: Radiation Injury
- 135: Electrical and Lightning Injury
- 136: Decompression Illness
SECTION XX: PEDIATRIC NEUROLOGY
- 137: Neonatal Neurology
- 138: Nervous System Formation and Malformation
- 139: Inherited Metabolic Diseases
- 140: Chromosomal Disorders and Disorders of DNA
- 141: The Floppy Infant
- 142: Disorders of Motor and Cognitive Development
- 143: Autism Spectrum Disorders
- 144: Mitochondrial Encephalomyopathies
- 145: Neurocutaneous Syndromes
- 146: Spinal Muscular Atrophies of Childhood
- 147: Muscular Dystrophies and Congenital Myopathies
- 148: Seizures and Epilepsies in Neonates and Children
- 149: Pediatric Stroke
- 150: Brain Tumors in Children
- 151: Pediatric Brain Injury and Shaken Baby Syndrome
- 152: Human Immunodeficiency Virus, Fetal Alcohol Syndrome, and Drug Effects
SECTION XXI: PSYCHIATRY AND NEUROLOGY
- 153: Psychosis
- 154: Mood Disorders
- 155: Anxiety Disorders, Posttraumatic Stress Disorder, and Obsessive-Compulsive Disorder
- 156: Somatic Symptom Disorders
SECTION XXII: RECOVERY AND END-OF-LIFE CARE
- 157: Neurologic Rehabilitation
- 158: End-of-Life and Palliative Care in Neurology
Clinical Value Prop: Why Read This?
Merritt’s Neurology remains a foundational clinical resource by bridging historical expertise with modern, evidence-based data. Busy practitioners will find the book’s visually driven style—rich with diagnostic algorithms, treatment flowcharts, and management checklists—ideal for rapid bedside or office reference.
Crucially, this edition provides numbered citations for all diagnostic and management recommendations, linking them directly to high-quality clinical trials and meta-analyses.
It also expands into modern frontiers, covering neuro-coronavirus disease, global health disparities, and emerging pharmacotherapies for previously untreatable conditions, ensuring clinicians stay current in a rapidly evolving field.
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